The Board consists of Secretaries to the following departments in ex-officio capacity; four nominated private members and Secretary, TDB as Member Secretary in ex-officio capacity:
- Prof. Umesh V. Waghmare , Secretary, Department of Science & Technology
- Dr. (Mrs.) N. Kalaiselvi, Secretary, Department of Scientific & Industrial Research
- Sh. Rajesh Kumar Singh, Secretary DDR&D and Chairman DRDO (Additional Charge)
- Sh. Vumlunmang Vualnam , Secretary, Department of Expenditure
- Sh. Amardeep Singh Bhatia, Secretary, Department for Promotion of Industry and Internal Trade
- Sh. Rohit Kansal, Secretary, Department of Rural Development
- Dr. Debashish Bhattacharjee, Former Vice President Technology and R&D, Tata Steel
- Ms. Padmaja Ruparel , Co-Founder, Indian Angel Network (IAN)
- Sh. Shriprakash Shukla, Chairman of the Boards in Mahindra Defence Systems, Mahindra Aerostructures and Mahindra Telephonics
- Ms. Vandana Gupta , Company Secretary and Compliance Management, Mitsubishi Corporation
- Sh. Rajesh Kumar Pathak, Secretary, Technology Development Board
