The Board consists of Secretaries to the following departments in ex-officio capacity; four nominated private members and Secretary, TDB as Member Secretary in ex-officio capacity:
Ex-officio
- Prof. Abhay Karandikar Secretary, DST & Chairman, TDB
- Dr. (Mrs.) N. Kalaiselvi Secretary, DSIR & DG, CSIR
- Dr. Samir V Kamat Secretary DDR&D and Chairman DRDO
- Dr. Manoj Govil Secretary Department of Expenditure
- Shri Amardeep Singh Bhatia Secretary, Department for Promotion of Industry and Internal Trade (DPIIT), Ministry of Commerce & Industry,
Government of India - Shri Shailesh Kumar Singh Secretary, Department of Rural Development
- Shri Pradeep Goyal Chairman, Pradeep Metals, Navi Mumbai
- Ms. Bineesha. P Executive Director, International Institute of Waste Management, Bangalore
- Prof. Manoj Kumar Dhar Director, Academy of Scientific and Innovative Research (AcSIR), Ghaziabad
- Dr. Mridul Hazarika Former Vice-Chancellor,University of Guwahati, Guwahati
- Shri Rajesh Kumar Pathak Secretary, TDB